Advanced General Organic Chemistry: A Modern Approach (Part I & II) by Sachin Kumar Ghosh, published by the New Central Book Agency

Name: Advanced General Organic Chemistry: A Modern Approach (Part I & II) by Sachin Kumar Ghosh, published by the New Central Book Agency - Booksbp.com
SKU: 9788173814419
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SKU: 9788173814419

📘 Part I: Foundations, Stereochemistry, & Core Mechanisms

Part I establishes the structural, energetic, and spatial principles needed to understand organic chemistry.

Nature of Bonding & Structures: Focuses on atomic orbitals, molecular orbital theory, delocalized chemical bonds, resonance, hyperconjugation, tautomerism, and hydrogen bonding.
Stereochemistry (Spatial Architecture): Comprehensive study of optical isomerism, chirality, enantiomers, diastereomers, racemic mixtures, resolution techniques, geometric isomerism (E/Z designations), and conformational analysis of acyclic and cyclic systems (like cyclohexane boat and chair forms).
Reaction Intermediates & Energetics: Covers the structure, stability, generation, and reactivity of key reactive intermediaries, including carbocations, carbanions, free radicals, carbenes, nitrenes, and arynes.
Fundamental Reaction Mechanisms: Explains kinetic vs. thermodynamic control, transition states, intermediates, Hammond’s postulate, isotope effects, and linear free-energy relationships (including the Hammett equation).
Aliphatic Nucleophilic Substitution (\(S_N1, S_N2, S_Ni\)): Structural effects, solvent effects, leaving group abilities, stereochemical outcomes, and neighboring group participation (NGP).

📙 Part II: Functional Groups, Synthesis, & Biomolecules

Part II moves into complex multi-step synthetic methods, structural classes, cyclic chemistry, and the chemistry of life.

Advanced Chemistry of Functional Groups: Comprehensive functional group properties and reactions for advanced oxygen, nitrogen, and sulfur-containing systems.
Hydrocarbons & Cyclic Systems: Reactivity patterns of aliphatic and aromatic pathways, including specific additions to active double bonds and ring systems.
Heterocyclic Compounds: Synthesis, structure, and chemical reactions of five- and six-membered heterocycles with one or more heteroatoms (such as furan, pyrrole, thiophene, and pyridine).
Synthetic Planning & Retrosynthesis: Systematic strategies for total synthesis, utilizing disconnection approaches, protection and deprotection of functional groups, and chemoselectivity.
Biomolecules & Organic Polymers:
- Carbohydrates: Ring structures, mutarotation, chain configuration adjustments, and structural analysis of mono- and disaccharides.
- Amino Acids & Proteins: Synthesis of amino acids, peptide linkages, primary/secondary/tertiary structures, and chemical peptide sequencing.
- Nucleic Acids: Chemical building blocks and bonding configurations of RNA and DNA.
Modern Additions & Appendices: Advanced text additions focusing on Phase Transfer Catalysts (PTC), Crown ethers, Sigmatropic rearrangements, Green Chemistry parameters, and an introductory guide to Mass Spectroscopy (MS