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Physiology Made Easy by author A.K. Basak, published by (NCBA) (New Central Book Agency).
Original price was: ₹750.00.₹600.00Current price is: ₹600.00.
Core Academic Topics Covered:-
This textbook functions as a comprehensive practical guide to bridge the gap between theoretical drug knowledge and laboratory execution. The primary topics include:
1. Laboratory Animal Handling & Ethical Guidelines
- Detailed study of common laboratory models including rodents (mice, rats, guinea pigs) and non-rodents (rabbits).
- Standard protocols for anesthesia, euthanasia, and routes of drug administration.
- Compliance guidelines set by regulatory frameworks such as CPCSEA (Committee for the Purpose of Control and Supervision of Experiments on Animals).
2. Pre-clinical & Screening Methodologies
- Methods to obtain preliminary efficacy, toxicity, and pharmacokinetic data for candidate drugs.
- Exploration of in vivo (whole living organism) and in vitro (isolated tissues/cells) bioassays.
3. Isolated Organ and Tissue Systems
- Traditional organ bath experiments tracking chemical responses (e.g., studying the behavior of smooth muscle, autonomic nervous system blockers, or receptor antagonists).
- Recording contractions and calculating drug potency metrics like ED₅₀ and LD₅₀.
4. Biostatistics & Computer-Simulated Alternatives
- Statistical methods utilized to correctly log data variations, ensure reliability, and accurately evaluate experimental groups.
- Introduction to computer-simulated learning programs used to substitute or mimic real animal models in modern educational scenarios.
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